How to Protect Yourself from Sexually Transmitted Diseases STDs
Valacyclovir hydrochloride, under the brand name Valtrex, is distributed by GlaxoSmithKline (GSK). It is the 3rd largest pharmaceutical company in the world, following Johnson & Johnson and Pfizer. Valtrex is an antiviral drug that works on some of the most sinister viruses known to man. It is used to treat existing infection and protect exposed individuals through prophylaxis.
According to clinical studies, valacyclovir hydrochloride has the most significant effect on herpes simplex virus type I (HSV-I) and herpes simplex virus type II (HSV-II). These viruses are the known causative agents of oral and genital herpes. Exposure to either of the two can result to oral herpes or genital herpes. However, basing from statistics, herpes simplex virus type I is the predominant causative agent for oral herpes. Herpes simplex virus type II is consequently the principal cause for genital herpes. Make no mistake, HSV-I can also cause genital herpes and HSV-II, oral herpes.
Unfortunately, herpes is still incurable to date. Valtrex for STDs is then used for treatment only, not cure. As a prodrug, Valtrex only works after it is metabolized by the body. Valacyclovir hydrochloride is an esterified form of acyclovir. It can only work after the esterases convert valacyclovir into acyclovir, its active form. The acyclovir is then further converted into a monophosphate compound by the viral thymidine kinase. Favorably, viral thymidine kinase is 3000 times more effective at phosphorylation compared to cellular thymidine kinase. The monophosphate still undergoes further phosphorylation to its active triphosphate form. These substances then bind with the viral DNA polymerase to create a termination in the chain. Viral enzymes cannot remove these phosphates, which consequently results to inhibition of further DNA polymerase activity.
Valtrex for STDs is most useful for prophylaxis, preventing transmission, and decreasing recurrence of symptoms. It is given to infected patients to lessen the chances of transmission, especially during active infection or “shedding” of the virus. During this time, there should be no sexual contact of any kind even when taking the drug. Valtrex for STDs are also often used for patients with compromised immunity—patients with HIV or undergoing chemotherapy. Prophylaxis is the purpose. This is because the lesser the immunity, the higher the chances are of contracting the incurable disease. It is also used for healthier patients (excluding the fact that they are infected with herpes) to reduce chances of recurrence of symptoms.
Aside from its action against HSV-I and II, Valtrex also works against varicella zoster virus, cytomegalovirus, and Epstein-Barr virus. These viruses cause chicken pox, shingles, infectious mononucleosis (kissing disease), and cytomegalovirus infection. It has also shown to be effective as prophylaxis for Herpes B virus.
Even though Valtrex for STDs, particularly oral and genital herpes, cannot provide a cure, its existence has helped millions of herpes sufferers throughout the world. Its higher bioavailability (which is about 55%) compared to its predecessor, acyclovir (with only 10% to 20%), has made it a key element in the revolution of herpes treatment. With Valtrex, herpes sufferers can lead a normal life with fewer worries about recurrences of the symptoms. In addition, the non-infected population can also be protected by taking the drug as prophylaxis if suspected to be exposed to the virus.